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Alice Johnson

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Dr Alice Johnson MChem, MRSC

Lecturer in Inorganic Chemistry

Summary

I joined 香蕉视频 as a lecturer in inorganic chemistry in 2022. My research focusses on the mechanism of action of metal complexes in the treatment of inflammatory diseases and I am a member of both the chemistry research group and the cancer research group within the Biomolecular Sciences 香蕉视频 Centre. I teach undergraduate and postgraduate students across the chemistry and biosciences degree programmes. I am a member of the Royal Society of Chemistry and Real Sociedad Española de Química and am currently the Early Career 香蕉视频er representative for the Industry and Innovation 香蕉视频 Institute.

Alice Johnson

About

I obtained my Master of Chemistry (MChem) at the University of Durham and as part of this undertook a research placement in Spain through the ERASMUS scheme. Following this I moved to the Institute of Chemical Synthesis and Homogenous Catalysis (ISQCH) at the University of Zaragoza, Spain, to complete a PhD in Inorganic Chemistry working on the synthesis and properties of novel organogold complexes under the supervision of Prof. M. Concepción Gimeno. Through this I gained significant experience in synthetic organometallic chemistry as well as in studies of luminescence and cytotoxicity of metal complexes. I also undertook research placements at Institute of Chemical 香蕉视频 of Catalonia (ICIQ) in Tarragona, Spain, working for Prof. Antonio Echavarren on the synthesis of novel gold catalysts, and at the Fundamental and Applied Heterochemistry Laboratory within the Paul Sabatier University in Toulouse, France, working for Prof. Didier Bourissou on gold carbene complexes.
Following completion of my PhD, I moved to the University of Oxford for a postdoctoral research position in the group of Prof. Andrew Weller where I worked on rhodium catalysed amine-borane dehydropolymerisation, including the isolation and characterisation of sigma-complexes and studies of rhodium nanoparticle catalysis. I then moved to the University of Leicester for a postdoctoral position in the group of Dr Rama Suntharalingam working on the synthesis of anti-cancer stem cell copper complexes. It was here I gained expertise in cell culture and cancer cell assays.
My current research focusses on the synthesis of novel metal complexes featuring bioactive ligands and the study of their mechanism of action in inflammatory diseases, including cancer.

Teaching

School of Biosciences and Chemistry

College of Health, Wellbeing and Life Sciences

Biosciences and Chemistry

BSc/MChem Chemistry, BSc/MSci Biochemistry, BSc Biomedical Science, MSc Analytical Chemistry, MSc Pharmaceutical Analysis

Introduction to Inorganic and Materials Chemistry; Physical and Inorganic Chemistry; Advanced Inorganic, Physical and Materials Chemistry; Frontiers of Chemical 香蕉视频; Professional and Scientific Practice; Bioanalytical Methods; Plant Physiology and Anatomy; Atoms to Molecules; Energy and Reactions; Advanced Laboratory and 香蕉视频 Practice; BSc 香蕉视频 Project; MSc 香蕉视频 Project; MChem 香蕉视频 Project

香蕉视频

Synthesis of novel metal complexes for the treatment of inflammatory diseases. Studies of the mechanism of action of metal based drugs in biological systems. New drug delivery approaches.

Publications

Journal articles

Singh, K., Singh, K., Johnson, A., & Suntharalingam, K. (2024). . European Journal of Inorganic Chemistry.

Johnson, A., Feng, X., Singh, K., Ortu, F., & Suntharalingam, K. (2023). . Molecules, 28 (17).

Cross, M., Brodie, C., Crivoi, D., Goodall, J., Ryan, D., Mart铆nez-Mart铆nez, A., ... Weller, A.S. (2023). . Chemistry (Weinheim an der Bergstrasse, Germany).

Johnson, A., Olelewe, C., Kim, J.H., Northcote-Smith, J., Mertens, R.T., Passeri, G., ... Suntharalingam, K. (2022). . Chemical Science.

Xiao, Z., Northcote鈥怱mith, J., Johnson, A., Singh, K., & Suntharalingam, K. (2022). . European Journal of Inorganic Chemistry.

Johnson, A., Iffland-M眉hlhaus, L., Northcote-Smith, J., Singh, K., Ortu, F., Apfel, U.-.P., & Suntharalingam, K. (2022). . Dalton Transactions.

Johnson, A., Royle, C.G., Brodie, C.N., Mart铆nez-Mart铆nez, A.J., Duckett, S.B., & Weller, A.S. (2021). . Inorg Chem, 60 (18), 13903-13912.

Johnson, A., Iffland, L., Singh, K., Apfel, U.-.P., & Suntharalingam, K. (2021). . Dalton Trans, 50 (17), 5779-5783.

Xiao, Z., Johnson, A., Singh, K., & Suntharalingam, K. (2021). The Discrete Breast Cancer Stem Cell Mammosphere Activity of Group 10鈥怋is(azadiphosphine) Metal Complexes. Angewandte Chemie, 133 (12), 6778-6783.

Xiao, Z., Johnson, A., Singh, K., & Suntharalingam, K. (2021). . Angewandte Chemie - International Edition, 60 (12), 6704-6709.

Johnson, A., Northcote-Smith, J., & Suntharalingam, K. (2021). . Trends in Chemistry, 3 (1), 47-58.

Northcote-Smith, J., Johnson, A., Singh, K., Ortu, F., & Suntharalingam, K. (2021). . Inorganics, 9 (1).

Kaur, P., Johnson, A., Northcote-Smith, J., Lu, C., & Suntharalingam, K. (2020). . ChemBioChem, 21 (24), 3618-3624.

Feld, C.J., Johnson, A., Xiao, Z., & Suntharalingam, K. (2020). . Chemistry, 26 (61), 14011-14017.

Johnson, A., & Gimeno, M.C. (2020). . Chemistry - A European Journal, 26 (49), 11256-11265.

Johnson, A., Marzo, I., & Gimeno, M.C. (2020). . Dalton Transactions, 49 (33), 11736-11742.

Eskandari, A., Kundu, A., Johnson, A., Karmakar, S., Ghosh, S., & Suntharalingam, K. (2020). . Dalton Transactions, 49 (14), 4211-4215.

Boyd, T.M., Andrea, K.A., Baston, K., Johnson, A., Ryan, D.E., & Weller, A.S. (2019). . Chemical Communications, 56 (3), 482-485.

Dietz, M., Johnson, A., Mart铆nez-Mart铆nez, A., & Weller, A.S. (2019). . Inorganica Chimica Acta, 491, 9-13.

Johnson, A., Mart铆nez-Mart铆nez, A.J., Macgregor, S.A., & Weller, A.S. (2019). . Dalton Trans, 48 (26), 9776-9781.

Johnson, A., Marzo, I., & Gimeno, M.C. (2018). . Chemistry - A European Journal, 24 (45), 11693-11702.

Johnson, A., & Gimeno, M.C. (2017). . Organometallics, 36 (7), 1278-1286.

Smirnova, E.S., Munoz Molina, J.M., Johnson, A., Bandeira, N.A.G., Bo, C., & Echavarren, A.M. (2016). ChemInform Abstract: Polynuclear Gold [AuI]4, [AuI]8, and Bimetallic [AuI4AgI] Complexes: C鈥擧 Functionalization of Carbonyl Compounds and Homogeneous Carbonylation of Amines. ChemInform, 47 (43).

Johnson, A., & Gimeno, M.C. (2016). An efficient and sustainable synthesis of NHC gold complexes. Chemical communications (Cambridge, England), 52 (62), 9664-9667.

Smirnova, E.S., Mu帽oz鈥匨olina, J.M., Johnson, A., Bandeira, N.A.G., Bo, C., & Echavarren, A.M. (2016). Polynuclear Gold [AuI]4, [AuI]8, and Bimetallic [AuI 4AgI] Complexes: C鈭扝 Functionalization of Carbonyl Compounds and Homogeneous Carbonylation of Amines. Angewandte Chemie, 128 (26), 7613-7617.

Smirnova, E.S., Mu帽oz Molina, J.M., Johnson, A., Bandeira, N.A.G., Bo, C., & Echavarren, A.M. (2016). . Angew Chem Int Ed Engl, 55 (26), 7487-7491.

Johnson, A., Laguna, A., & Gimeno, M.C. (2014). Axially chiral allenyl gold complexes. Journal of the American Chemical Society, 136 (37), 12812-12815.

Mart铆n-Lasanta, A., 脕lvarez de Cienfuegos, L., Johnson, A., Miguel, D., Mota, A.J., Orte, A., ... Cuerva, J.M. (n.d.). Novel ortho-OPE metallofoldamers: binding-induced folding promoted by nucleating Ag(i)鈥揳lkyne interactions. Chem. Sci, 5 (12), 4582-4591.

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