Professor Charmaine Childs PhD
Professor of Clinical Science
Summary
As Professor of Clinical Science, I have experience in leading a broad programme of research in human trauma and surgery. Working in universities in the UK and overseas, my focus is translational research. In recognition of my scientific work, I have received six international awards in the field of burns, brain trauma, surgery and wound infection.
I currently lead the Applied Imaging research theme for the Centre for Applied Health and Social Care 香蕉视频.
About
After qualifying, care of burned children inspired my research interests. I received National/International recognition winning a number of scientific prizes in paediatric trauma. Later, as an MRC scientist, I led the metabolic research programme on childhood burns. Building a bespoke calorimeter to measure energy expenditure, our ‘metabolic-cart’ became the prototype for later commercial systems.
By 2000, injured brain became my research focus. Pioneering new, implantable, brain sensors, the objective was to forge new ways to reduce secondary, ischaemic brain damage. Results were controversial, challenging existing dogma, specifically on brain temperature.
In 2009, invited to the National University of Singapore, I explored new invasive and non-invasive imaging modalities for sepsis, brain-injury diagnosis and wound infection. Back in the UK, my research programme combines my interests of non-invasive imaging diagnosis in trauma; the injured body (with a focus on surgical site infection) and, as we enter an era of brain injury awareness, the injured brain; specifically concussion in sport. Most recently my research path has reached another fork in my scientific journey, applying my imaging skills in the field of endovascular revascularisation.
Within Health and Social Care 香蕉视频, I lead the Applied Imaging theme.
香蕉视频 Interests: TRAUMA and SURGERY
• Vascular assessment and perfusion imaging
• Surgical site infection
• Severe traumatic brain injury and neurocritical care
• Concussion in sports
• Human thermoregulation: fever and brain cooling
• Sepsis
IMAGING
Invasive multiparameter neuromonitoring (temperature, pressure and oxygen content), 1HMR spectroscopy, long wave dynamic infrared thermography, Optical Coherence Tomography (OCT), Automated Pupillometry.
香蕉视频 Interests: TRAUMA and SURGERY
- Surgical site infection
- Severe traumatic brain injury and neurocritical care
- Concussion in sports
- Human thermoregulation: fever and brain cooling
- Prognostic performance of serum biomarkers
- Sepsis
IMAGING
Advanced, invasive multiparameter neuromonitoring (temperature, pressure and oxygen content)
Non-invasive Imaging
- Magnetic resonance spectroscopy (1HMRS) and imaging (1HMRSI)
- Non-invasive infra-red thermal imaging
- Optical coherence tomography (OCT) and retinal imaging.
香蕉视频
Current research funded by:
Medical 香蕉视频 Council UK
Innovate UK
/research/specialisms/health-and-social-care-research/news/new-methods-to-measure-brain-temperature
/research/in-action/projects/thermal-imaging
Collaborations and partnerships:
Current Academic Partners: La Trobe University, Melbourne Australia
Commercial Partner: PyrOptik Instruments Ltd
Publications
Key Publications
Childs, C., Sandy-Hodgetts, K., Broad, C., Cooper, R., Manresa, M., & Verd煤-Soriano, J. (2020). Birth-related wounds. Journal of Wound Care, 29, 1-48.
Journal articles
Usman, J.E., Morley, A., Childs, C., Rogerson, D., & Klonizakis, M. (2024). . Healthcare, 12 (19).
Usman, J.E., Childs, C., Rogerson, D., & Klonizakis, M. (2024). . Healthcare, 12 (9).
Roscoe, S., Skinner, E., Kabucho Kibirige, E., Childs, C., Weekes,, C.E., Wootton, S., ... Stavroulakis, T. (2023). . Clinical Nutrition ESPEN.
Kirk, C., & Childs, C. (2023). . Vision, 7 (2).
Childs, C., Nwaizu, H., Bullivant, E., Willmott, J., Davies, M., Ousey, K., ... Jacques, R. (2023). . International Journal of Environmental 香蕉视频 and Public Health, 20 (6).
Usman, J.E., Childs, C., Rogerson, D., & Klonizakis, M. (2022). . International Journal of Environmental 香蕉视频 and Public Health, 19 (14).
Usman, J.E., Childs, C., Rogerson, D., & Klonizakis, M. (2022). . International Journal of Environmental 香蕉视频 and Public Health, 19 (14).
Tamang, P., Childs, C., Stephenson, J., & Ousey, K. (2022). . Wounds UK, 18 (2), 11-18.
Yi, C.Y., Childs, C., Peng, C., & Robinson, D. (2021). . Building and Environment.
Childs, C., Elliott, J., Khatab, K., Hampshaw, S., Fowler-Davis, S., Willmott, J., & Ali, A. (2020). Thermal Sensation in Older People, with and without Dementia, Living in Residential Care: New Assessment Approaches Using Infrared Thermography. .
Childs, C., & Soltani, H. (2020). . International Journal of Environmental 香蕉视频 and Public Health, 17 (22).
Childs, C., Elliott, J., Khatab, K., Hampshaw, S., Fowler-Davis, S., Willmott, J.R., & Ali, A. (2020). . International Journal of Environmental 香蕉视频 and Public Health 鈥 Open Access Journal, 17 (18), e6932.
Saednia, K., Tabbarah, S., Lagree, A., Wu, T., Klein, J., Garcia, E., ... Tran, W. (2020). . Journal of Medical Imaging and Radiation Sciences, 51 (3), S3.
Saednia, K., Tabbarah, S., Lagree, A., Wu, T., Klein, J., Garcia, E., ... Tran, W. (2020). . International Journal of Radiation Oncology*Biology*Physics, 106 (5), 1071-1083.
Siah, C.J., Childs, C., Chia, C.K., & Cheng, K.-.F.K. (2019). . Journal of clinical nursing, 28 (11-12), 2285-2295.
Cleary, M., Raeburn, T., West, S., & Childs, C. (2019). Contemporary nurse.
Childs, C., Wright, N., Willmott, J., Davies, M., Kilner, K., Ousey, K., ... Stephenson, J. (2019). . Antimicrobial resistance and infection control, 8 (7).
Childs, C., Barker, L.A., Gage, A.M.D., & Loosemore, M. (2018). Investigating possible retinal biomarkers ofhead trauma in Olympic boxers using opticalcoherence tomography. Eye and Brain, 10, 101-110.
Marshall, M., Deo, R., Childs, C., & Ali, A. (2018). . The Journal of neuroscience nursing, 1.
Kornhaber, R., Childs, C., & Cleary, M. (2018). . Burns, 44 (5), 1026-1039.
Tran, W.T., Childs, C., Probst, H., Farhat, G., & Czarnota, G.J. (2018). . Journal of Medical Imaging and Radiation Sciences, 49 (4), 342-351.
Tran, W.T., Gangeh, M.J., Sannachi, L., Chin, L., Watkins, E., Bruni, S.G., ... Czarnota, G.J. (2017). . British journal of cancer, 116 (10), 1329-1339.
Childs, C., Siraj, M.R., Fair, F., Selvan, A., Soltani, H., Wilmott, J., & Farrell, R. (2016). . Journal of wound care, 25 (9), 499-512.
Tran, W.T., Childs, C., Chin, L., Slodkowska, E., Sannachi, L., Tadayyon, H., ... Czarnota, G.J. (2016). . Oncotarget, 7 (15), 19762-19780.
Siah, C.J.R., & Childs, C. (2015). . Journal of wound care, 24 (3), 112-120.
Childs, C., & Shen, L. (2015). . Critical Care, 19 (1), 267.
Lim, S.-.F., Ong, S.Y., Tan, Y.L., Ng, Y.S., Chan, Y.H., & Childs, C. (2015). . International Journal of Clinical Practice, 69 (4), 422-428.
Mart铆nez-Morillo, E., Childs, C., Garc铆a, B.P., 脕lvarez Men茅ndez, F.V., Romaschin, A.D., Cervellin, G., ... Diamandis, E.P. (2015). . Clinical Chemistry and Laboratory Medicine, 53 (10), 1575-1584.
Childs, C., Wang, L., Neoh, B.K., Goh, H.L., Zu, M.M., Aung, P.W., & Yeo, T.T. (2014). . Journal of Medical Engineering & Technology, 38 (7), 339-350.
Lesko, M.M., O鈥橞rien, S.J., Childs, C., Bouamra, O., Rainey, T., & Lecky, F. (2014). . Brain Injury, 28 (7), 987-994.
Yeeles, H., Trinick, S., Childs, C., Soltani, H., & Farrell, T. (2014). Open Journal of Obstetrics and Gynecology, 4 (9), 547-549.
Childs, C., Ong, Y.T., Zu, M.M., Aung, P.W., Cheung, C.Y., & Kuan, W.S. (2014). . European Journal of Emergency Medicine, 21 (5), 388-389.
Mattar, I., Chan, M.F., & Childs, C. (2013). . ISRN Critical Care, 2013.
Childs, C., Liu, K., Vail, A., & Pan, J. (2013). . International Journal of Statistics in Medical 香蕉视频, 2 (1), 14-22.
Lesko, M.M., Jenks, T., Perel, P., O'Brien, S., Childs, C., Bouamra, O., & Lecky, F. (2013). . Journal of Neurotrauma, 30 (24), 2021-2030.
Childs, C., Mart铆nez-Morillo, E., Wai, A.P., Zu, M.M., Diamandis, A., & Diamandis, E.P. (2013). . Clinical Chemistry and Laboratory Medicine, 51 (9), e195-e197.
Lim, S.F., & Childs, C. (2013). . International Journal of Nursing Studies, 50 (7), 1004-1010.
Childs, C., & Lunn, K. (2013). . Critical Care, 17 (2), 222.
Vescovo, E., Levick, A., Childs, C., Machin, G., Zhao, S., & Williams, S.R. (2013). . NMR in Biomedicine, 26 (2), 213-223.
Lim, D.A.F.N., Chan, M., & Childs, C. (2013). . Critical Care, 17 (1), R5.
Lesko, M.M., Jenks, T., O'Brien, S.J., Childs, C., Bouamra, O., Woodford, M., & Lecky, F. (2013). . Journal of Neurotrauma, 30 (1), 17-22.
Childs, C., Zu, M.M., Wai, A.P., Tsai, Y.T., Wu, S., & Li, W. (2012). . Engineering, 4 (10B), 53-56.
Childs, C., Wai, A.P., Zu, M.M., Nga, V.D.W., Sun, I.S., Kejia, T., ... Yeo, T.T. (2012). . Brain Injury, 26 (9), 1163.
Siah, C.J., & Childs, C. (2012). . Journal of wound care, 21 (3), 124, 126-30.
Childs, C., Ng, A.L.C., Liu, K., & Pan, J. (2011). . Brain Injury, 25 (12), 1163-1169.
Lesko, M.M., Rainey, T., Childs, C., Bouamra, O., O鈥橞rien, S., & Lecky, F. (2010). . Injury Extra, 41 (12), 156-157.
Sacho, R.H., Vail, A., Rainey, T., King, A.T., & Childs, C. (2010). . Journal of Neurotrauma, 27 (12), 2157-2164.
Childs, C., Wieloch, T., Lecky, F., Machin, G., Harris, B., & Stocchetti, N. (2010). . Frontiers in Neurology, 1 (146).
Childs, C. (2010). . Nursing And Health Sciences, 12 (3), 284-286.
Lesko, M.M., Woodford, M., White, L., O'Brien, S.J., Childs, C., & Lecky, F.E. (2010). . BMC Medical 香蕉视频 Methodology, 10 (1), 72.
Machin, G., & Childs, C. (2010). . Journal of Medical Engineering & Technology, 34 (3), 192-199.
Childs, C. (2009). . Burns, 35 (1), 158.
Childs, C., & Machin, G. (2009). . Critical Care, 13 (4), R106.
Childs, C., Sacho, R.H., & King, A.T. (2009). . Neurosurgery, 64 (6), E1206.
Kirk, D., Rainey, T., Vail, A., & Childs, C. (2009). . Critical Care, 13 (3), R81.
Rainey, T., Lesko, M., Sacho, R., Lecky, F., & Childs, C. (2009). . Resuscitation, 80 (3), 341-345.
Childs, C. (2008). . British Journal of Neurosurgery, 22 (4), 486-496.
Sacho, R.H., & Childs, C. (2008). . British Journal of Neurosurgery, 22 (4), 497-507.
Childs, C., Jones, A.K.P., & Tyrrell, P.J. (2008). . Brain Injury, 22 (7-8), 603-609.
Kauppinen, R.A., Vidyasagar, R., Childs, C., Balanos, G.M., & Hiltunen, Y. (2008). . NMR in Biomedicine, 21 (4), 388-395.
Khojasteh, V.J., Edwards-Jones, V., Childs, C., & Foster, H.A. (2007). . Burns, 33 (3), 334-340.
Leach, P., Childs, C., Evans, J., Johnston, N., Protheroe, R., & King, A. (2007). . British Journal of Neurosurgery, 21 (1), 11-15.
Childs, C., Hiltunen, Y., Vidyasagar, R., & Kauppinen, R.A. (2007). . Magnetic Resonance in Medicine, 57 (1), 59-66.
Childs, C., Vail, A., Leach, P., Rainey, T., Protheroe, R., & King, A. (2006). . Neurocritical Care, 5 (1), 10-14.
Johnston, N.J., King, A.T., Protheroe, R., & Childs, C. (2006). . Resuscitation, 70 (2), 254-262.
Childs, C., Vail, A., Protheroe, R., King, A.T., & Dark, P.M. (2005). . Anaesthesia, 60 (8), 759-765.
Soop, M., Duxbury, H., Agwunobi, A.O., Gibson, J.M., Hopkins, S.J., Childs, C., ... Carlson, G.L. (2002). . American journal of physiology. Endocrinology and metabolism, 282 (6), E1276-85.
Childs, C., Renshaw, A., Dunn, K.W., & Davenport, P.J. (2001). . Burns, 27 (4), 386-388.
Renshaw, A., & Childs, C. (2000). . Burns, 26 (8), 750-753.
Edwards-Jones, V., Dawson, M.M., & Childs, C. (2000). . Burns, 26 (4), 323-333.
Childs, C., Harrison, R., & Hodkinson, C. (1999). . Archives of Disease in Childhood, 80 (3), 262-266.
Childs, C., Goldring, S., Tann, W., & Hillier, V.F. (1998). . Archives of Disease in Childhood, 79 (3), 251-255.
Childs, C. (1998). Burns, 24 (1), 29-33.
Childs, C. (1998). . Burns, 24 (1), 25-28.
Edwards-Jones, V., Childs, C., & Foster, H.A. (1996). . Burns, 22 (5), 384-9.
Wright, I.P., Griffiths, M., & Childs, C. (1995). . Anaesthesia, 50 (10), 875-878.
Jenney, M.E., Childs, C., Mabin, D., Beswick, M.V., & David, T.J. (1995). . Archives of Disease in Childhood, 72 (2), 144-146. doi:10.1136/adc.72.2.144
Childs, C., Edwards-Jones, V., Heathcote, D.M., Dawson, M., & Davenport, P.J. (1994). . Burns, 20 (6), 514-521.
Childs, C. (1994). . Burns, 20 (4), 291-300.
Childs, C., & Little, R.A. (1994). . Archives of Disease in Childhood, 71 (1), 31-4.
Childs, C. (1993). . Archives of disease in childhood, 68 (5), 658-661.
Childs, C., Stoner, H.B., & Little, R.A. (1992). . Clinical science (London, England : 1979), 83 (1), 117-126.
McGuinness, K., & Childs, C. (1991). . Clinical Physics and Physiological Measurement, 12 (4), 343-351.
Childs, C., Hall, T., Davenport, P.J., & Little, R.A. (1990). . Burns, 16 (6), 418-422.
Childs, C., Heath, D.F., Little, R.A., & Brotherston, M. (1990). . Archives of emergency medicine, 7 (3), 135-147.
Bianchi, A., Bruce, J., Cooper, A.L., Childs, C., Kohli, M., Morris, I.D., ... Rothwell, N.J. (1989). . Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et m茅tabolisme, 21 (11), 640-641.
Childs, C., & Little, R.A. (1988). . Burns, 14 (5), 343-348.
Childs, C. (1988). . Burns, 14 (1), 1-6.
Childs, C. (1982). . Nursing focus, 4 (4), 6-7.
Conference papers
Kirk, C., Maden-Wilkinson, T., & Childs, C. (2023). Pilot Pupillometry Data Examining The Effects Of Mixed Martial Arts Sparring On Autonomic Brain Function. MEDICINE & SCIENCE IN SPORTS & EXERCISE, 55 (9), 489-490.
Kirk, C., & Childs, C. (2023). A case study of automated pupillometry changes over a 48-hour period following mixed martial arts sparring (Oral presentation and abstract). In BASES Conference 2023, Coventry, 16 November 2023 - 17 November 2023.
Kirk, C., Maden-Wilkinson, T., & Childs, C. (2023). Pilot Pupillometry Data Examining The Effects Of Mixed Martial Arts Sparring On Autonomic Brain Function. Medicine & Science in Sports & Exercise, 55 (9S), 489-490.
Kirk, C., Maden-Wilkinson, T., & Childs, C. (2023). Pilot data of the effects of mixed martial arts sparring on autonomic brain function (Oral presentation and abstract). In ECSS Annual Congress 2023, Paris, 4 July 2023 - 7 July 2023.
Roscoe, S., Skinner, E., Allen, S., Childs, C., Weekes, E., McDermott, C., & Stavroulakis, T. (2022). . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (Sup 1), 148-149.
Roscoe, S., Skinner, E., Allen, S., Childs, C., Weekes, E., McDermott, C., & Stavroulakis, T. (2022). . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (Sup 1), 148-149.
Marshall, M., Deo, R., Childs, C., & Ali, A. (2018). . International Journal of Stroke, 13 (3), 49.
Gwillt, A., Homer, C., Sherriff, G., & Childs, C. (2015). . In Britt, H., Morgan, L., & Walton, K. (Eds.) Futurescan 3: Intersecting Identities, 11 November 2015 - 12 November 2015. Creative and Print Services, Loughborough University
Childs, C., Gwilt, A., Sherriff, G., & Homer, C. . In Christer, K. (Ed.) Design 4 health: Proceedings of the 3rd European Conference on Design4Health, (pp. 1-9). Sheffield: 香蕉视频
Book chapters
Childs, C. (2018). . (pp. 467-482). Elsevier:
Selvan, A., & Childs, C. (2017). . In Ng, E.Y.K., & EtehadTavakol, M. (Eds.) Application of Infrared to Biomedical Sciences. (pp. 377-394). Springer:
Selvan, A., & Childs, C. (2017). . In Ng, E.Y.K., & Etehad Tavakol, M. (Eds.) Application of Infrared to Biomedical Sciences. (pp. 377-394). Springer
Gwilt, A., Homer, C., Sherriff, G., & Childs, C. (2016). . In Futurescan 3 : Intersecting Identities. Creative and Print Services:
Childs, C. (1998). The acute response to burn injury in children. In Injury in the Young. Cambridge University Press
Theses / Dissertations
Tran, W.T. (2018). . (Doctoral thesis). Supervised by Childs, C., Probst, H., & Czarnota, G.
Other publications
Cronin De Chavez, A., Childs, C., Kelly, S., Tod, A., & Burke, D. (2013). . BMJ Publishing Group:
Other activities
External responsibilities:
Peer review include:
Science, Acta Neurochirurgica, Buildings and Environment, Journal of Wound Care, Frontiers, Critical Care Medicine, Nursing and Health Sciences.
GRANT FUNDING Bodies include: NIHR, The Dunhill MedicalTrust
Postgraduate supervision
Multiparametric monitoring of breast tumour response to neoadjuvant chemotherapy using quantitative ultrasound and diffuse optical imaging. Director of Studies
Role of retinal imaging as a biomarker for concussion and mild traumatic brain injury in contact sports.
Director of StudiesBiomarkers and prognostic value in predicting incidence of delirium in elderly ICU patients
Primary Supervisor, National University of Singapore
Constipation in Patients with Stroke: Incidence, Associated Risk Factors and Management at a Tertiary Hospital in Singapore :
National University of Singapore, Primary Supervisor
Longitudinal Analysis of Physiological Data from Critically Ill Patients”.
University of Manchester, UK Co-supervisor
Emergency Medicine Training Fellow. Prognostic models of traumatic brain injury: Models of Mortality Probability in Severe Traumatic Brain Injury.
University of Manchester, UK Co-supervisor
Cerebral and Systemic Responses to Whole body cooling in patients with traumatic brain injury
University of Manchester UK, Primary supervisor
Brain temperature, inflammation and Outcome after Severe Traumatic Brain injury
University of Manchester, UK Primary supervisorMedia
Charmaine is Professor of Clinical Science and is an expert in critical illness, human trauma, and non-invasive imaging modalities. Her current work focuses on skin perfusioin imaging in lower limb vascular disease.
Professor Childs is also undertaking innovative research in a number of fields, including using infra-red thermal imaging for wound assessment after surgery, retinal imaging and automated pupillometry in sports concussion.
Charmaine is a member of the executive of the Sheffield Multimodal Imaging Centre (SMIC).
Science