Dr Danny Allwood PhD, MChem, MRSC, FHEA
Senior Lecturer in Organic Chemistry
Summary
My research interests span synthetic organic and medicinal chemistry as well as brewing science and chemical analysis of brewing ingredients and beer. My teaching covers all aspects of organic chemistry, NMR spectroscopy and brewing science.
About
I completed my undergraduate education at the University of Warwick (MChem Chemistry) in 2008. I then moved to the University of Cambridge to undertake PhD studies, funded by Cancer 香蕉视频 UK and supervised by Prof Steven V. Ley. I completed my doctorate in 2012 and stayed in the Ley group to conduct three years of postdoctoral research funded by Pfizer Global 香蕉视频 and Development. In 2015, I moved to 香蕉视频 as a Lecturer in Organic and Medicinal Chemistry before being promoted to Senior Lecturer in Organic Chemistry in 2018. Since 2022, I have been course leader for the BSc/MChem Chemistry degree streams.
Synthetic chemistry
Organic methodology
Catalysis
Medicinal chemistry
Teaching
Biosciences and Chemistry
Courses taught:
BSc/MChem Chemistry, BSc/MSci Biochemistry, MSc Analytical Chemistry, MSc Pharmaceutical Analysis, MSc Pharmacology and Biotechnology.
Modules taught:
Fundamentals of Organic Chemistry, Organic and Biological Chemistry, Advanced Organic Synthesis and Spectroscopy, Medicinal Chemistry and Drug Discovery, Advanced Organic Spectroscopy, Fundamentals of Microbial Biotechnology, Frontiers of Chemical 香蕉视频, Professional and Scientific Practice, Advanced Laboratory and 香蕉视频 Practice, Level 6 香蕉视频 Project, MSc 香蕉视频 Project, MChem 香蕉视频 Project.
香蕉视频
Development of new synthetic methodologies. Synthesis of medicinally relevant compounds. In silico guided drug discovery. Brewing analysis.
T.M. Beale, D.M. Allwood, A. Bender, P.J. Bond, J.D. Brenton, D.S. Charnock-Jones, S.V. Ley, R.M. Myers*, J.W. Shearman, J. Temple, J. Unger, C.A. Watts and J. Xian, ACS Med. Chem. Lett., 2012, 3, 177-181.
D.M. Allwood*, D.C. Blakemore, A.D. Brown and S.V. Ley, J. Org. Chem., 2014, 79, 328-338.
D.M. Allwood, D.L. Browne and S.V. Ley*, Org. Synth., 2014, 91, 162-174.
D.M. Allwood*, D.C. Blakemore and S.V. Ley, Org. Lett., 2014, 16, 3064-3067.
R.R. Merchant, D.M. Allwood*, D.C. Blakemore and S.V. Ley, J. Org. Chem., 2014, 79, 8800-8811.
G. Rouquet, D.E. Moore, M. Spain, D.M. Allwood, C. Battilocchio, D.C. Blakemore, P.V. Fish, S. Jenkinson, A.S. Jessiman, S.V. Ley, G. McMurray and R.I. Storer*, ACS Med. Chem. Lett. 2015, 6, 329-333.
C. Battilocchio*, F. Feist, A. Hafner, M. Simon, D.N. Tran, D.M. Allwood, D.C. Blakemore and S.V. Ley*, Nature Chem. 2016, 8, 360-367.
A.J. Chappell*, D.M. Allwood, R. Johns, S. Brown, K. Sultana, A. Anand and T. Simper, J. Int. Soc. Sports Nutr. 2018, 15, 42.
T. Simper*, M. Gilmartin, D.M. Allwood, L. Taylor and A.J. Chappell, Nutrition and Health, 2019, 25, 265 274.
A.J. Chappell*, D.M. Allwood and T.N. Simper, J. Diet. Suppl., 2020, 17, 249 260.
T.L. Wootton and D.M. Allwood*, Org. Biomol. Chem., 2022, 20, 2255-2260.
Publications
Key Publications
Wootton, T., & Allwood, D. (2022). . Organic and Biomolecular Chemistry.
Battilocchio, C., Feist, F., Hafner, A., Simon, M., Tran, D., Allwood, D., ... Ley, S. (2016). . Nature Chemistry, 8 (4), 360-363.
Merchant, R.R., Allwood, D.M., Blakemore, D.C., & Ley, S.V. (2014). Regioselective preparation of saturated spirocyclic and ring-expanded fused pyrazoles. The Journal of organic chemistry, 79 (18), 8800-8811.
Allwood, D., Blakemore, D.C., & Ley, S.V. (2014). . Organic Letters, 16 (11), 3064-3067.
Allwood, D., Blakemore, D.C., Brown, A.D., & Ley, S.V. (2014). . The Journal of Organic Chemistry, 79 (1), 328-338.
Journal articles
O鈥橞rien, A., Zhang, H., Allwood, D.M., & Rawsthorne, A. (2024). . Modelling, 5 (1), 201-222.
Simper, T., Gilmartin, M., Allwood, D., Taylor, L., & Chappell, A. (2019). . Nutrition and Health.
Chappell, A., Allwood, D., & Simper, T. (2018). . The Journal of Dietary Supplements.
Chappell, A., Allwood, D., & Simper, T. (2018). . Journal of the International Society of Sports Nutrition, 15 (1), 42.
Rouquet, G., Moore, D.E., Spain, M., Allwood, D., Battilocchio, C., Blakemore, D.C., ... Storer, R.I. (2015). . ACS Medicinal Chemistry Letters, 6 (3), 329-333.
Merchant, R.R., Allwood, D.M., Blakemore, D.C., & Ley, S.V. (2015). ChemInform Abstract: Regioselective Preparation of Saturated Spirocyclic and Ring鈥怑xpanded Fused Pyrazoles. ChemInform, 46 (12).
Allwood, D.M., Blakemore, D.C., & Ley, S.V. (2014). ChemInform Abstract: Preparation of Unsymmetrical Ketones from Tosylhydrazones and Aromatic Aldehydes via Formyl C鈥擧 Bond Insertion. ChemInform, 45 (48).
Allwood, D.M., Blakemore, D.C., Brown, A.D., & Ley, S.V. (2014). ChemInform Abstract: Metal鈥怓ree Coupling of Saturated Heterocyclic Sulfonylhydrazones with Boronic Acids. ChemInform, 45 (23).
Allwood, D., Browne, D.L., & Ley, S.V. (2014). . Organic Syntheses, 91, 162-174.
Allwood, D.M., Browne, D.L., & Ley*, S.V. (2014). Synthesis and Use of a Trifluoromethylated Azomethine Ylide Precursor: Ethyl 1鈥怋enzyl鈥 trans 鈥5鈥(trifluoromethyl)pyrrolidine鈥3鈥恈arboxylate. .
Beale, T.M., Allwood, D.M., Bender, A., Bond, P.J., Brenton, J.D., Charnock-Jones, D.S., ... Xian, J. (2012). A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles. ACS medicinal chemistry letters, 3 (3), 177-181.
Theses / Dissertations
Wootton, T.L. (2024). . (Doctoral thesis). Supervised by Allwood, D., Aberdein, N., & Princivalle, A.
Slater, J.E. (2024). . (Doctoral thesis). Supervised by Allwood, D., Hamilton, A., & Miller, K.
Presentations
Campbell, S. (2017). Brewing 鈥 Art, Science or Magic? Presented at: Sheffield Festival of Science and Engineering, Sentinel Brewhouse
Postgraduate supervision
Currently supervising doctoral students in BMRC and NCEFE on projects based in medicinal chemistry and brewing analysis.